Biosketch

Stéphane Zaffran, PhD.
DR1 INSERM
Aix Marseille Université

Degrees :

• 1993 Master, Cell Biology, Aix Marseille University, France
• 1993-1997 PhD., Cell Biology, Aix Marseille University, France
• 2005 Habilitation (HDR), Biology, Paris 7 University, Paris, France

Appointments

• 1997-2001 Postdoctoral Research Fellow, The Mount Sinai School of Medicine, New York, NY, USA - Mentor Pr. M. Frasch
• 2001-2002 Postdoctoral Research Fellow, The Pasteur Institute, Paris, France Mentor - Pr. M. Buckingham
• 2002-2006 Researcher Fellow, CNRS CR1 Department of Developmental Biology, Pasteur Institute, Paris
• 2006-2008 Researcher Fellow, CNRS CR1 Institute of Developmental Biology of Marseille-Luminy, Marseille
• 2008-2009 Principal Investigator, CNRS CR1, Medical Genetics & Functional Genomics, Marseille
• 2009-2017 Principal Investigator, INSERM DR2, Medical Genetics & Functional Genomics, U910 Inserm, Marseille
• 2015-2017 Deputy Director, Medical Genetics & Functional Genomics, U910 Inserm, Marseille
• 2018-2023 Principal Investigator, INSERM DR2, Marseille Medical Genetics Center, U1251 Inserm, Marseille
• 2018-2023 Head of the Departement of Cardiovascular Development and Pathology, Marseille Medical Genetics Center
• 2024-present Principal Investigator, INSERM DR1, Marseille Medical Genetics Center, U1251 Inserm, Marseille
• 2024-present Deputy Director, Marseille Medical Genetics Center

Publications PubMed

Publications from PubMed

Book Chapters and other Publications not listed in PubMed

Rochais, F, Kelly RG, Zaffran S. (2019). Développement et régénération cardiaque. Editors: GRRC (John Libbey Eurotext, France).

Zaffran S. (2018). Cardiac growth: Cardiomyocyte polarisation. In The ESC Textbook of cardiovascular development. Editors: JM. Perez-Pomares, R. Kelly, pp. 86-93. Oxford University Press, Oxford.

Zaffran S, Bajolle F. (2017). Genetics and developmental basis of the bicuspid aortic valve. Arch Mal Coeur Vaiss. 256:22-26.

Laforest B, Zaffran S. (2016). Genetics of conotruncal anomalies. In Surgery of conotruncal anomalies. Editors: F. Lacour-Gayet, T. Spray, E. Bove, V. Hraska, V Morrel, pp. 607-621. Springer International Publishing, Switzerland.

Zaffran S, Niederreither K. (2015). Retinoic acid signaling and heart development. In The Retinoids: Biology, Biochemistry, and Disease. Editors: P Dollée, K Niederreither, pp.353-369. Wiley-Blackwell, New Jersey, USA.

Zaffran S, El Robrini N, Bertrand N. (2014). Retinoids and Cardiac Development. J. Dev. Biol. 2, 50-71.

Laforest B, Bertrand N, Zaffran S. (2014). Anterior Hox Genes in Cardiac Development and Great Artery Patterning. J. Cardiovasc. Dev. Dis. 1, 3-13.

Ryckebusch L, Zaffran. (2009). Embryonic dysfunction and congenital heart diseases. Arch Mal Coeur Vaiss, 174(15), 28-32.

Bajolle F, Bertrand N, Zaffran S. (2007). Développement du système cardiovasculaire. Traité de cardiologie et des maladies cardiovasculaires. Editeurs: J-Y Artigou, J-J Monsuez, eds. (Paris, France, Masson).

Bonnet D, Bajolle F, Zaffran S. (2006). Mécanismes embryologiques et génétique des cardiopathies. Med Feot Ech Gyn, 68, 17-19.

Kelly R-G, Zaffran S, Buckingham M, Brown N. (2005). Fgf10 and the embryological origin of outflow tract myocardium. In Cardiovascular Development and Congenital Malformations, M. Artman, D. W. Benson, D. Strivastava, and M. Nakazawa, eds. (Oxford, UK, Blackwell Futura).

Lee H-H, Zaffran S, Frasch M. (2004). The development of the larva visceral musculature of Drosophila. In Muscle Development in Drosophila. H Sink, ed. (Georgetown, TX, USA, Landes Bioscience Collection).

Zaffran S. (2003). Early cardiac development in vertebrates and invertebrates. Proc Indian Natn Sci Acad B, Biol Sci 69, (5), 703-718.